Nigel Calcutt, PhD USA Professor, Department of Pathology | UC San Diego Health Sciences

Nigel Calcutt

Pathological Mechanisms of Diabetic Neuropathy and Neuropathic Pain

Tuesday, 29 June | 08:15–08:40


Nigel Calcutt, PhD is Professor, Department of Pathology at UC San Diego Health Sciences in California, USA. His research is focused on mechanisms of peripheral nerve disease and the identification of new therapeutic approaches to prevent onset of neuropathy or alleviate symptoms of an existing neuropathy such as sensory loss or pain. Most students and Fellows in his laboratory work on cellular and animal models of diabetic neuropathy although they also have projects looking at the toxic neuropathies that are side effects of certain cancer drugs and at models of HIV-associated peripheral neuropathy. He has adopted a multi-disciplinary approach to addressing the etiology of diabetic neuropathy and applies a diverse array of techniques that range from molecular and biochemical investigations of fundamental disease mechanisms to physiologic and behavioral assessments of nerve function and the efficacy of potential therapeutic strategies. He also collaborates with a number of biotechnology and pharmaceutical companies, so that the etiologic mechanisms that they propose can be tested by rational drug design and in vivo pharmacology and ultimately by clinical trials.